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1.
Fisioterapia (Madr., Ed. impr.) ; 45(5): 239-246, sept.- oct. 2023.
Article in Spanish | IBECS | ID: ibc-225284

ABSTRACT

Objetivo Evaluar cuantitativamente el efecto de la técnica manual de fisioterapia sobre el volumen endometrial y los valores del histograma en participantes infértiles. Métodos Estudio piloto, analítico, intervencionista, con grupo control, desarrollado en la Clínica Juana Crespo sobre 34 participantes infértiles. Se midió el volumen endometrial y subendometrial del útero, los índices de vascularización (IV%), el índice de flujo de vascularicación (IVF%) y el índice de flujo (IF%) mediante ultrasonografía Doppler 3D, después de aplicar la técnica manual de movilización de tejidos blandos de las fosas ilíacas. Resultados En el grupo experimental la comparación de los volúmenes endometriales totales antes (M=41,09) y después de la aplicación de la técnica fisioterápica (M=47,29) presentó diferencias estadísticamente significativas, z=–3,946 (p<0,001), r=–0,73, al igual que el estudio de los histogramas, alcanzando diferencias significativas en el índice de flujo (IF%) entre los registros pre (M=35,22) y post (M=37,62), z=–2,849 (p<0,005), r=–52. El índice de flujo de vascularización (IFV%) y el índice de vascularización (IV%) no tuvieron diferencias significativas entre el tiempo pre y post. Los histogramas IV%, IF%, IFV% indican p<0,005. Conclusiones La técnica de fisioterapia aumenta los volúmenes endometriales totales y el IF% endometrial después de su aplicación, aunque no varían las variables IV% e IFV% (AU)


Objective To quantitatively assess the effect of physical therapy manual technique on endometrial volume and histogram values in infertile participants. Methods Pilot, analytical, interventional study, with a control group, developed at the Juana Crespo Clinic on 34 infertile participants. The endometrial and subendometrial volume of the uterus, Vascularization Indices (VI%), Vascularization Flow Index (VFI%) and Flow Index (IF%) were measured by 3D Doppler Ultrasonography, after applying the manual mobilization technique in soft tissue of the iliac fossa. Results In the experimental group, the comparison of the total endometrial volumes before (M=41.09) and after the application of the physiotherapy technique (M=47.29) presented statistically significant differences, z=-3.946 (p<0.001), r=-, 73, like the study of histograms, reaching significant differences in the flow index (IF%) between the pre (M=35.22) and post (M=37.62) records, z=-2.849 (p<0.005), r=- 52. The vascularization flow index (IFV%) and the vascularization index (IV%) did not have significant differences between the pre and post time. Histograms IV%, IF%, IFV% indicate p<0.005. Conclusions The physiotherapy technique increases the total endometrial volumes and the endometrial IF% after its application, although the IV% and IFV% variables do not vary (AU)


Subject(s)
Humans , Female , Musculoskeletal Manipulations/methods , Infertility, Female/rehabilitation , Regional Blood Flow , Uterine Artery , Endometrium/blood supply , Endometrium/diagnostic imaging , Treatment Outcome , Pilot Projects
2.
Femina ; 51(8): 497-501, 20230830. ilus
Article in Portuguese | LILACS | ID: biblio-1512463

ABSTRACT

O presente estudo tem como objetivo relatar o caso de uma paciente com malformação arteriovenosa uterina, efetivamente tratada com embolização seletiva e com fertilidade preservada. A malformação arteriovenosa uterina é uma alteração vascular rara até então pouco descrita na literatura. A paciente do sexo feminino apresentou quadro de sangramento uterino anormal, com início 30 dias após um abortamento, sem realização de curetagem, de uma gestação resultante de fertilização in vitro. Foram, então, realizados exames de imagem, que levaram ao diagnóstico de malformação arteriovenosa uterina. O tratamento de escolha foi a embolização arterial seletiva, com resolução do caso. Após sete meses, nova fertilização in vitro foi realizada, encontrando-se na 36a semana de gestação. São necessários mais estudos sobre essa malformação a fim de que sejam estabelecidos os métodos mais eficazes para o manejo de casos futuros, especialmente quando há desejo de gestar.


The present study aims to report the case of a patient with uterine arteriovenous malformation, effectively treated with selective embolization and with preserved fertility. Uterine arteriovenous malformation is a rare vascular disorder that has so far been rarely described in the literature. Female patient presented with abnormal uterine bleeding, starting 30 days after an abortion without subsequent curettage, of a pregnancy resulting from in vitro fertilization. Imaging tests were then performed that led to the diagnosis of uterine arteriovenous malformation. The treatment of choice was selective arterial embolization, with successful results. After seven months, a new in vitro fertilization was performed, being in the 36th week of pregnancy. Further studies on this pathology are needed in order to establish the most effective methods for the management of future cases, especially when there is a desire to become pregnant.


Subject(s)
Humans , Female , Pregnancy , Adult , Arteriovenous Malformations/drug therapy , Arteriovenous Malformations/diagnostic imaging , Uterine Hemorrhage/drug therapy , Uterus/diagnostic imaging , Case Reports , Diagnostic Imaging , Women's Health , Endometritis/drug therapy , Uterine Artery Embolization/instrumentation , Adenomyosis/drug therapy , Gynecology , Infertility, Female/complications , Obstetrics
3.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 50(1): 100797-100797, Ene-Mar. 2023. ilus
Article in Spanish | IBECS | ID: ibc-214993

ABSTRACT

El sangrado uterino anormal (SUA) es una de las patologías ginecológicas más comunes en mujeres en edad reproductiva. El sistema de clasificación de la Federación Internacional de Ginecología y Obstetricia (PALM-COEIN) armoniza las definiciones de los síntomas de hemorragia normal y anormal y clasifica las posibles causas subyacentes en causas estructurales y no estructurales. El objetivo de este manuscrito es revisar el diagnóstico radiológico de cada una de las causas estructurales de sangrado uterino anormal, examinar las indicaciones de las técnicas de radiología vascular intervencionista en el manejo del SUA y conocer el procedimiento de embolización de arterias uterinas, así como sus posibles complicaciones y contraindicaciones.(AU)


Abnormal uterine bleeding is one of the most common gynaecological pathologies in women of reproductive age. The classification system of the International Federation of Gynaecology and Obstetrics (PALM-COEIN) harmonizes the definitions of normal and abnormal bleeding symptoms and classifies possible underlying causes as structural and non-structural. The aim of this manuscript is to review the radiological diagnosis of each of the structural causes of abnormal uterine bleeding, to examine the indications for interventional vascular radiology techniques in the treatment of abnormal uterine bleeding, and to learn about the uterine artery embolization procedure, as well as its possible complications and contraindications.(AU)


Subject(s)
Humans , Female , Radiology, Interventional/methods , Uterine Hemorrhage/diagnostic imaging , Uterine Diseases , Leiomyoma , Adenomyosis , Angiography , Uterine Artery Embolization , Gynecology , Obstetrics
4.
Radiol. bras ; 55(4): 231-235, Aug. 2022. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1394559

ABSTRACT

Abstract Objective: To evaluate the safety and efficacy of using highly compressible calibrated microspheres in uterine artery embolization (UAE) for the treatment of uterine fibroids. Materials and Methods: This was a prospective multicenter study. Thirty-two women with symptomatic uterine fibroids were selected for UAE between January 2019 and March 2020. The participants completed the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire, underwent contrast-enhanced pelvic magnetic resonance imaging (MRI), and were submitted to anti-Müllerian hormone measurement, subsequently undergoing UAE with Embosoft microspheres. After six months, the patients again completed the UFS-QOL questionnaire and underwent pelvic MRI. Results: The most common symptoms were abnormal uterine bleeding (in 81.3% of the cases), pelvic pain (in 81.3%), and compression (in 46.9%). Of the 32 patients evaluated, 12 (37.5%) had anemia due to abnormal uterine bleeding. Thirty patients completed the study. Among those patients, we observed median reductions of 21.4% in uterine volume and 15.9% in dominant fibroid volume. We identified no adverse events that could be attributed to the material itself, although there were events attributed to the UAE procedure in general. Conclusion: For the treatment of uterine fibroids, UAE using Embosoft microspheres shows satisfactory results, providing reductions in uterine and dominant fibroid volumes, with a low rate of adverse events, and improving patient quality of life, as well as demonstrating safety and efficacy.


Resumo Objetivo: Avaliar a eficácia e segurança da embolização da artéria uterina (EAU) com microesferas calibradas de alta compressibilidade no tratamento de miomas uterinos. Materiais e Métodos: Este foi um estudo prospectivo e multicêntrico. Foram selecionadas 32 mulheres com miomas uterinos sintomáticos para EAU de janeiro de 2019 a março de 2020. As participantes preencheram o questionário Uterine Fibroid Symptom and Quality of Life (UFS-QOL), realizaram ressonância magnética (RM) pélvica com contraste e teste para medição dos hormônios antimüllerianos, seguido de embolização de miomas com microesferas Embosoft. Após seis meses, as pacientes novamente preencheram o UFS-QOL e realizaram RM pélvica. Resultados: Os sintomas mais relatados foram sangramento uterino anormal (81,3%), dor pélvica (81,3%) e compressão (46,9%). Doze pacientes (37,5%) apresentaram anemia consequente a sangramento uterino anormal. Nas 30 pacientes que completaram o estudo, observou-se redução mediana de 21,4% no volume uterino e 15,9% no volume do mioma dominante. Não foram identificados eventos adversos possivelmente relacionados ao material utilizado, apenas em relação ao procedimento de EAU. Conclusão: EAU com microesferas Embrosoft mostrou resultados satisfatórios no tratamento de miomas uterinos, com redução dos volumes uterino e do mioma dominante, baixa taxa de eventos adversos e melhora na qualidade de vida, demonstrando segurança e eficácia.

5.
Rev. bras. ginecol. obstet ; 44(3): 231-237, Mar. 2022. tab, graf
Article in English | LILACS | ID: biblio-1387874

ABSTRACT

Abstract Objective To analyze whether acetylsalicylic (ASA) intake modifies the mean uterine arteries pulsatility index (UtA-PI) at the 2nd or 3rd trimester in a cohort of pregnant women with abnormal mean UtA-PI at between 11 and 14 weeks of gestation. Methods This is a retrospective cohort study. Singleton pregnancies with abnormal mean UtA-PI at between 11 and 14 weeks of gestation were studied. The participants were divided into 3 groups: 1) If the participant did not take ASA during pregnancy; 2) If the participant took ASA before 14 weeks of gestation; and 3) If the participant took ASA after 14 weeks of gestation. The mean UtA-PI was evaluated at the 2nd and 3rd trimesters, and it was considered to improve when it decreased below the 95th percentile. The prevalence ratio (PR) and the number needed to treat (NNT) werecalculated. Results A total of 72 participants with a mean UtA-PI>95th percentile at the 1st trimester of gestation were evaluated. Out of the 18 participants who took ASA, 8 participants started it before 14 weeks of gestation and 10 after. A total of 33.3% of these participants had improved the mean UtA-PI at the 2nd and 3rd trimesters of gestation, although it was not statistically significant (p=0.154). The prevalence ratio was 0.95 (95% confidence interval [CI]: 0.31-1.89), but between the 1st and 2nd trimesters of gestation, the PR was 0.92 (95%CI: 0.21-0.99) and it was statistically significant. Conclusion The present work demonstrates a modification of the mean UtA-PI in participants who took ASA compared with those who did not. It is important to check if ASA can modify the normal limits of uterine arteries because this could have an impact on surveillance.


Resumo Objetivo Analisar se a ingestão de acetilsalicílico (ASA) modifica o índice médio de pulsatilidade das artérias uterinas (UtA-PI) no 2° ou 3° trimestre em uma coorte de gestantes com média anormal de UtA-PI entre 11 e 14 semanas. Métodos Este é um estudo de coorte retrospectivo. Gravidezes únicas com média anormal de UtA-PI entre 11 e 14 semanas foram estudadas. As participantes foram divididas em 3 grupos: 1) Se a participante não tomou ASA durante a gravidez, 2) Se a participante tomou AAS antes das 14 semanas e 3) Se a participante tomou ASA após 14 semanas. A média do UtA-PI foi avaliada nos 2° e 3° trimestres e considerou-se que melhorava quando diminuía<95° percentil. Foram calculados a razão de prevalência (RP) e o número necessário para tratar (NNT). Resultados Foram avaliadas 72 participantes com média de UtA-PI>95° percentil no 1° trimestre de gravidez. Das 18 participantes que tomaram ASA, 8 participantes começaram antes de 14 semanas e 10 depois. Um total de 33,3% desses participantes melhoraram a média de UtA-PI nos 2° e 3° trimestres, embora não tenha sido estatisticamente significante (p=0,154). A razão de prevalência foi de 0,95 (intervalo de confiança [IC95%]: 0,31-1,89), mas entre os 1° e o 2° trimestres, a RP foi de 0,92 (IC95%: 0,21-0,99) e foi estatisticamente significativa. Conclusão O presente trabalho demonstra uma modificação da média de UtA-PI em participantes que faziam uso de ASA em comparação com aqueles que não faziam. É importante verificar se o ASA pode modificar os limites normais das artérias uterinas porque isso pode ter um impacto na vigilância.


Subject(s)
Humans , Female , Pregnancy , Pre-Eclampsia/prevention & control , Aspirin/therapeutic use , Ultrasonography , Ultrasonography, Doppler, Color , Uterine Artery/diagnostic imaging
6.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 48(4): [100672], Oct.-Dic. 2021. tab, ilus
Article in English | IBECS | ID: ibc-220365

ABSTRACT

Objective: To present a case series of 26 patients with postpartum hemorrhages treated with vascular ligations and analyze its efficiency for hemorrhagic control.Material and methods: This case series included patients with postpartum hemorrhages hospitalized in a high risk pregnancy unit in Sofia Feldman Hospital, Brazil, between January 2014 and May 2017, who were treated with vascular ligation techniques. The data were collected from patient medical records.Results: The success rate in hemorrhagic control was 96.2% and hemorrhagic control of the single case in which vascular ligation failed was obtained with total hysterectomy. Hypovolemic shock occurred in 19.2% of the patients and blood transfusion was required in 26.9%. No patient required intensive care unit treatment. Hypertensive syndrome was the most prevalent comorbidity (46.2%). The main etiology was uterine atony (65.4%). Uterine and/or pelvic adhesions and uterine lacerations associated with fetal extraction occurred in 19.3% and 15.4% of cases, respectively. Conclusion: Vascular ligations are efficient strategies for hemorrhagic control during cesarean sections and should be an integral part of the set of techniques that allow uterus preservation in the treatment of postpartum hemorrhage.(AU)


Objetivo: Presentar una serie de casos de 26 pacientes con hemorragias posparto tratadas con ligaduras vasculares y analizar su eficacia para el control hemorrágico. Material y métodos: Esta serie de casos incluyó a pacientes con hemorragias posparto hospitalizadas en la Unidad de Embarazo de Alto Riesgo del Hospital Sofia Feldman, Brasil, entre enero de 2014 y mayo de 2017, que fueron tratadas con técnicas de ligaduras vasculares. Los datos se obtuvieron de los registros médicos de las pacientes. Resultados: La tasa de éxito en el control hemorrágico fue del 96,2% y el control hemorrágico del caso único en el que falló la ligadura vascular, se obtuvo con histerectomía total. El choque hipovolémico ocurrió en el 19,2% de los pacientes y se requirió transfusión de sangre en el 26,9%. Ningún paciente requirió tratamiento en la Unidad de Cuidados Intensivos. El síndrome hipertensivo fue la comorbilidad con mayor prevalencia (46,2%). La principal etiología fue la atonía uterina (65,4%). Las adherencias uterinas y/o pélvicas y las laceraciones uterinas asociadas con la extracción fetal ocurrieron en el 19,3% y el 15,4% de los casos, respectivamente. Conclusión: Las ligaduras vasculares son estrategias eficaces para el control hemorrágico durante la cesárea y deben integrar el conjunto de técnicas que permiten la preservación del útero en el tratamiento de la hemorragia posparto.(AU)


Subject(s)
Humans , Female , Treatment Outcome , Inpatients , Physical Examination , Symptom Assessment , Ligation , Postpartum Hemorrhage , Uterine Artery , Fertility Preservation , Gynecology , Obstetrics , Brazil
7.
MedUNAB ; 24(3): 375-383, 202112.
Article in Spanish | LILACS | ID: biblio-1353532

ABSTRACT

Introducción. La preeclampsia es la primera causa de muerte materna directa en Colombia y la segunda a nivel mundial. El desarrollo de estrategias de predicción y prevención puede disminuir las complicaciones y secuelas ocasionadas por dicha enfermedad. El Doppler de arterias uterinas entre las semanas 11 y 13+6 como prueba independiente o en combinación con factores maternos o pruebas bioquímicas permite tasas de detección de preeclampsia temprana ≥ 90% a partir de la implementación de distintos cribados. La validez de dicha prueba diagnóstica presenta una sensibilidad del 47.8% y especificidad del 92.1% para la detección de preeclampsia temprana; con una sensibilidad del 26.4% y especificidad del 93.4% para predecir preeclampsia en cualquier etapa. División de los temas tratados. En esta revisión de tema se aborda la utilidad de esta medición, se habla de la realización de la técnica en cuestión y, por último, se revisan las herramientas estandarizadas que están disponibles en la actualidad junto con su accesibilidad y precisión. Conclusiones. La evidencia empírica que respalda la validez de las herramientas disponibles hoy en día para el tamizaje de preeclampsia a través de la evaluación por ultrasonografía Doppler de las arterias uterinas es significativa. Al ser Colombia un país que presenta una prevalencia alta de preeclampsia, conocer la utilidad de esta medición favorece una vigilancia temprana y oportuna, lo que disminuye los posibles desenlaces desfavorables para las maternas.


Introduction. Preeclampsia is the primary cause of direct maternal death in Colombia and the second globally. The development of prediction and prevention strategies can reduce complications and consequences caused by this disease. The uterine arteries Doppler between weeks 11 and 13+6 as an independent test or in combination with maternal factors or biochemical tests allows for early detection rates for preeclampsia of ≥90% from the implementation of different sieving. The validity of this diagnostic test has a sensitivity of 47.8% and specificity of 92.1% for the early detection of preeclampsia; with a sensitivity of 26.4% and specificity of 93.4% to predict preeclampsia at any stage. Division of Covered Topics. This topic review covers the usefulness of this measurement. It discusses the performance of the technique in question and, lastly, the standardized tools currently available are reviewed together with the accessibility and accuracy. Conclusions. The empirical evidence that supports the validity of the tools available today for the screening of preeclampsia via Doppler ultrasound evaluation of the uterine arteries is significant. As Colombia is a country with a high prevalence of preeclampsia, knowing the usefulness of this measurement favors early and timely surveillance, which reduces possible unfavorable outcomes for mothers.


Introdução. A pré-eclâmpsia é a principal causa de morte materna direta na Colômbia e a segunda no mundo. O desenvolvimento de estratégias de predição e prevenção pode reduzir as complicações e sequelas causadas pela doença. O Doppler da artéria uterina entre as semanas 11 e 13+6 como um teste independente ou em combinação com fatores maternos ou testes bioquímicos permite taxas de detecção de pré-eclâmpsia precoce≥90% a partir da implementação de diferentes exames. A validade desse teste diagnóstico tem sensibilidade de 47,8% e especificidade de 92,1% para a detecção de pré-eclâmpsia precoce; com uma sensibilidade de 26,4% e especificidade de 93,4% para prever pré-eclâmpsia em qualquer fase. Divisão dos tópicos abordados. Esta revisão de tópicos aborda a utilidade desta medição, discute a realização da técnica em questão e, por fim, são revisadas as ferramentas padronizadas que estão disponíveis atualmente, juntamente com sua acessibilidade e precisão. Conclusões. A evidência empírica que apoia a validade das ferramentas disponíveis atualmente para rastreamento de pré-eclâmpsia por meio da avaliação de ultrassom Doppler das artérias uterinas é significativa. Como a Colômbia é um país com alta prevalência de pré-eclâmpsia, conhecer a utilidade dessa medição favorece a vigilância precoce e oportuna, o que reduz possíveis resultados desfavoráveis para mulheres maternas.


Subject(s)
Ultrasonography, Prenatal , Pre-Eclampsia , Prenatal Care , Prenatal Diagnosis , Ultrasonography , Uterine Artery , Fetal Growth Retardation , Noninvasive Prenatal Testing
8.
Rev. bras. ginecol. obstet ; 43(12): 904-910, Dec. 2021. tab, graf
Article in English | LILACS | ID: biblio-1357085

ABSTRACT

Abstract Objective To evaluate the mean uterine artery pulsatility index (UtAPI) in each trimester of pregnancy as a predictor of early or late pre-eclampsia (PE) in Colombian pregnant women. Methods The UtAPI was measured in singleton pregnancies in each trimester. Uterine artery pulsatility index as predictor of PE was evaluated by odds ratio (OR), receiver operating characteristic (ROC) curves, and Kaplan-Meier diagram. Results Analysis in the 1st and 3rd trimester showed that abnormal UtAPI was associated with early PE (OR: 5.99: 95% confidence interval [CI]: 1.64-21.13; and OR: 10.32; 95%CI: 2.75-42.49, respectively). Sensitivity and specificity were 71.4 and 79.6%, respectively, for developing PE (area under the curve [AUC]: 0.922). The Kaplan-Meier curve showed that a UtAPI of 0.76 (95%CI: 0.58-1.0) in the 1st trimester was associated with early PE, and a UtAPI of 0.73 (95%CI: 0.55-0.97) in the 3rd trimester was associated with late PE. Conclusion Uterine arteries proved to be a useful predictor tool in the 1st and 3rd trimesters for early PE and in the 3rd trimester for late PE in a pregnant population with high prevalence of PE.


Resumo Objetivo Avaliar o índice médio de pulsatilidade da artéria uterina (UtAPI) em cada trimestre da gravidez como preditor de pré-eclâmpsia (PE) precoce ou tardia em gestantes colombianas. Métodos O UtAPI foi medido em gestações únicas em cada trimestre. O UtAPI como preditor de PE foi avaliado por odds ratio (OR), curvas receiver operating characteristic (ROC) e diagrama de Kaplan-Meier. Resultados A análise no 1° e 3° trimestres mostrou que um UtAPI anormal foi associado com PE inicial (OR: 5,99; intervalo de confiança [IC] 95%: 1,64-21,13; OR: 10,32; IC95%: 2,75-42,49, respectivamente). A sensibilidade e a especificidade foram de 71,4 e 79,6%, respectivamente, para o desenvolvimento de PE (area under the curve [AUC]: 0,922). A curva de Kaplan-Meier mostrou que um UtAPI de 0,76 (IC95%: 0,58- 1,0) no 1° trimestre foi associado com PE precoce, e que um UtAPI de 0,73 (IC95%: 0,55-0,97) no 3° trimestre foi associado com PE tardia. Conclusão As artérias uterinas mostraram ser uma ferramenta preditora útil no 1° e 3° trimestres para PE inicial e no 3° trimestre para PE tardia em uma população de gestantes com alta prevalência de PE.


Subject(s)
Humans , Female , Pregnancy , Pre-Eclampsia , Uterine Artery/diagnostic imaging , Pregnancy Trimester, First , Pulsatile Flow , Biomarkers , ROC Curve , Ultrasonography, Prenatal , Placenta Growth Factor
9.
Rev. bras. ginecol. obstet ; 43(4): 323-328, Apr. 2021. tab, graf
Article in English | LILACS | ID: biblio-1280047

ABSTRACT

Abstract Complete hydatidiform mole (CHM) is a rare type of pregnancy, in which 15 to 20% of the cases may develop into gestational trophoblastic neoplasia (GTN). The diagnostic of GTN must be done as early as possible through weekly surveillance of serum hCG after uterine evacuation.We report the case of 23-year-old primigravida, with CHM but without surveillance of hCG after uterine evacuation. Two months later, the patient presented to the emergency with vaginal bleeding and was referred to the Centro de Doenças Trofoblásticas do Hospital São Paulo. She was diagnosed with high risk GTN stage/score III:7 as per The International Federation of Gynecology and Obstetrics/World Health Organization (FIGO/WHO). The sonographic examination revealed enlarged uterus with a heterogeneous mass constituted of multiple large vessels invading and causing disarrangement of the myometrium. The patient evolved with progressive worsening of vaginal bleeding after chemotherapy with etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) regimen. She underwent blood transfusion and embolization of uterine arteries due to severe vaginal hemorrhage episodes, with complete control of bleeding. The hCG reached a negative value after the third cycle, and there was a complete regression of the anomalous vascularization of the uterus as well as full recovery of the uterine anatomy. The treatment in a reference center was essential for the appropriate management, especially regarding the uterine arteries embolization trough percutaneous femoral


Resumo Mola hidatiforme completa (MHC) é um tipo raro de gravidez, na qual 15 a 20% dos casos podem desenvolver neoplasia trofoblástica gestacional (NTG). O diagnóstico de NTG deve ser feito o mais cedo possível, pelo monitoramento semanal do hCG sérico após esvaziamento uterino. Relatamos o caso de uma paciente primigesta, de 23 anos de idade, com MHC, sem vigilância de hCG após esvaziamento uterino. Dois meses depois, a paciente compareceu na emergência com sangramento vaginal, sendo encaminhada ao Centro de Doenças Trofoblásticas do Hospital São Paulo, onde foi diagnosticada com NTG de alto risco, estádio e score de risco III:7 de acordo com a The International Federation of Gynecology and Obstetrics/Organização Mundial de Saúde (FIGO/OMS). O exame ultrassonográfico revelou útero aumentado com uma massa heterogênea constituída pormúltiplos vasos volumosos invadindo e desestruturando o miométrio. A paciente evoluiu com piora progressiva do sangramento vaginal após quimioterapia com o regime etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO). Ela foi submetida a transfusão de sangue e embolização das artérias uterinas devido aos episódios graves de hemorragia vaginal, com completo controle do sangramento. O hCG atingiu valor negativo após o terceiro ciclo, havendo regressão completa da vascularização uterina anômala, assim como recuperação da anatomia uterina. O tratamento em um centro de referência permitiu o manejo adequado, principalmente no que se refere à embolização das artérias uterinas através da punção percutânea da artéria femoral, que foi crucial para evitar a histerectomia, permitindo a cura da NTG e a manutenção da vida reprodutiva.


Subject(s)
Humans , Female , Pregnancy , Young Adult , Arteriovenous Malformations/complications , Uterine Hemorrhage/therapy , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Gestational Trophoblastic Disease/complications , Gestational Trophoblastic Disease/drug therapy , Embolization, Therapeutic , Uterine Hemorrhage/etiology , Uterine Hemorrhage/diagnostic imaging , Vincristine/therapeutic use , Methotrexate/therapeutic use , Ultrasonography, Prenatal , Pregnancy, High-Risk , Cyclophosphamide/therapeutic use , Dactinomycin/therapeutic use , Gestational Trophoblastic Disease/diagnostic imaging , Etoposide/therapeutic use , Uterine Artery
10.
Rev. méd. Minas Gerais ; 31: 31401, 2021.
Article in Portuguese | LILACS | ID: biblio-1291279

ABSTRACT

A Hemorragia Pós-parto é a maior causa mundial de histerectomia periparto. Sua abordagem terapêutica deve ser efetuada por uma sucessão de procedimentos farmacológicos e cirúrgicos antes de se recorrer à histerectomia. O acretismo placentário se apresenta como a etiologia de hemorragia pós-parto que mais dificulta a preservação uterina. Sua incidência se relaciona estritamente com a elevação contemporânea das taxas de cesárea, com os demais procedimentos cirúrgicos no útero e com a implantação segmentar da placenta. Com isso, objetiva-se relatar um caso de placenta prévia central e increta tratado por meio de excisão miometrial segmentar com reconstrução da parede uterina durante cesariana. A abordagem cirúrgica foi instituída seguindo os passos de localização per-operatória da placenta, realização de histerotomia corporal alta transversa, extração fetal, confirmação clínica do incretismo placentário, manutenção da placenta in situ, ligadura bilateral dos ramos ascendentes das artérias uterinas, ressecção de todo o segmento uterino anterior invadido por cotilédones placentários, reconstrução da parede uterina, histerorrafia, salpingotripsia bilateral, revisão da cavidade abdominal e laparorrafia. A técnica cirúrgica adotada foi eficiente na obtenção do controle hemorrágico durante a cesariana e não foi associada a complicações per ou pós-operatórias.


Postpartum Hemorrhage is the largest worldwide cause of peripartum hysterectomy. Its therapeutic approach must be performed by a succession of pharmacological and surgical procedures prior to hysterectomy. Placental accreta presents as the etiology of postpartum haemorrhage that makes uterine preservation more difficult. Its incidence is strictly related to the contemporary elevation of cesarean rates, other surgical procedures in the uterus and segmentar implantation of the placenta. We aim to report a case of central and increta placenta treated through segmental myometrial excision with reconstruction of the uterine wall during cesarean section. The surgical approach was instituted following the perioperative localization of the placenta, transverse corporal hysterotomy, fetal extraction, clinical confirmation of placental invasive aspects, maintenance of the placenta in situ, bilateral ligation of the uterine artery ascending branches, resection of the all anterior uterine segment invaded by placental cotyledons, reconstruction of the uterine wall, hysterorrhaphy, bilateral salpingotripsy, revision of the abdominal cavity and laparorrhaphy. The surgical technique adopted was efficient in obtaining hemorrhagic control during cesarean section and was not associated with per or postoperative complications.


Subject(s)
Humans , Female , Pregnancy , Placenta Accreta , Placenta Previa , Postpartum Hemorrhage , Hysterectomy , Surgical Procedures, Operative , Uterus , Cesarean Section , Uterine Artery , Peripartum Period , Ligation
11.
Ginecol. obstet. Méx ; 89(12): 956-962, ene. 2021. tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1375560

ABSTRACT

Resumen OBJETIVO: Identificar las complicaciones maternas durante la cesárea en pacientes con preeclampsia severa. MATERIALES Y MÉTODOS: Estudio retrospectivo, transversal y descriptivo efectuado en pacientes embarazadas con preeclampsia severa atendidas en la Unidad Médica de Alta Especialidad del Hospital de Gineco-Obstetricia 3 del Centro Médico Nacional La Raza entre el 1 de septiembre de 2020 y el 31 de mayo del año 2021. Se registraron: la indicación de la cirugía (materna o feto-placentaria), las complicaciones y su desenlace, el tiempo de estancia en la unidad de cuidados intensivos y en hospitalización y la muerte materna. Se utilizó estadística descriptiva con el programa estadístico SPSS v 20. RESULTADOS: Se estudiaron 100 pacientes con media de edad de 30.5 ± 5.85 años (límites 17 y 43), mediana de la paridad 2 (límites 1 y 6), semanas de embarazo 33.08 ± 3.9 (límites 26 y 39.4), peso 77.98 ± 15.87 kg (límites 42 y 120), talla 1.57 ± 0.07 m (límites 1.36 y 1.73) e IMC 31.46 ± 5.54 (límites 22.15 y 48.44). 90 de ellas finalizaron el embarazo por cesárea indicada por: crisis hipertensiva (81%), síndrome HELLP (17%), eclampsia (2%) y feto-placentaria en 10% (estado fetal no confiable 5%, ruptura prematura de las membranas 2%, anhidramnios 2%, restricción del crecimiento 1%). Se registraron 12% de complicaciones (atonía uterina (6%), lesión de una arteria uterina (2%), desgarro de la comisura de la histerorrafia (1%), hematoma de la histerorrafia (1%), hematoma del ligamento ancho (1%) y sangrado en capa (1%). Todas las complicaciones se corrigieron en el mismo tiempo quirúrgico. La media del tiempo entre el ingreso a hospitalización hasta la finalización del embarazo fue de 6.26 ± 2.26 horas, estancia en cuidados intensivos 1.36 ± 0.69 días y muerte materna 0%. CONCLUSIÓN: La frecuencia de complicaciones fue baja, quizá por tratarse de pacientes intervenidas en un hospital de alta especialidad.


Abstract OBJECTIVE: To identify maternal complications during cesarean section in patients with severe preeclampsia. MATERIALS AND METHODS: Retrospective, cross-sectional, descriptive study carried out in pregnant patients with severe preeclampsia attended at the High Specialty Medical Unit of the Obstetrics and Gynecology Hospital 3 of the National Medical Center La Raza between September 1, 2020 and May 31, 2021. The following were recorded: indication for surgery (maternal or feto-placental), complications and their outcome, length of stay in the intensive care unit and hospitalization, and maternal death. Descriptive statistics were used with the statistical program SPSS v 20. RESULTS: 100 patients were studied with mean age 30.5 ± 5.85 years (limits 17 and 43), median parity 2 (limits 1 and 6), weeks of pregnancy 33.08 ± 3.9 (limits 26 and 39.4), weight 77.98 ± 15.87 kg (limits 42 and 120), height 1.57 ± 0.07 m (limits 1.36 and 1.73) and BMI 31.46 ± 5.54 (limits 22.15 and 48.44). Ninety of them terminated the pregnancy by cesarean section indicated by: hypertensive crisis (81%), HELLP syndrome (17%), eclampsia (2%) and feto-placental in 10% (unreliable fetal status 5%, premature rupture of membranes 2%, anhydramnios 2%, growth restriction 1%). There were 12% complications (uterine atony (6%), uterine artery injury (2%), hysterorrhaphy commissure tear (1%), hysterorrhaphy hematoma (1%), broad ligament hematoma (1%) and layer bleeding (1%). All complications were corrected within the same surgical time. The mean time from hospitalization to termination of pregnancy was 6.26 ± 2.26 hours, intensive care stay 1.36 ± 0.69 days and maternal death 0%. CONCLUSION: The frequency of complications was low, perhaps because these patients underwent surgery in a high specialty hospital.

12.
Femina ; 49(4): 246-250, 2021. ilus
Article in Portuguese | LILACS | ID: biblio-1224100

ABSTRACT

Hemorragia pós-parto é a maior causa de histerectomia periparto. Esta revisão descreve e ilustra as técnicas de ligaduras vasculares utilizadas no tratamento cirúrgico da hemorragia pós-parto. São apresentados os detalhes técnicos da ligadura das artérias uterinas, da ligadura das conexões útero-ovarianas, da ligadura tríplice de Tsirulnikov, das ligaduras sequenciais de AbdRabbo e de Morel e da ligadura das artérias ilíacas internas. Também são revistos os fatores que dificultam o sucesso dessas técnicas. As ligaduras vasculares são estratégias eficientes para o controle hemorrágico durante cesarianas e devem integrar o conjunto de técnicas que preservam o útero no tratamento da hemorragia pós-parto.(AU)


Postpartum hemorrhage is the major cause of peripartum hysterectomy. This review describes and illustrates the techniques of vascular ligations used in the surgical treatment of postpartum hemorrhage. The technical details of the uterine arteries ligation, of the ligation of the utero-ovarian connections, of the Tsirulnikov triple ligation, of the AbdRabbo and Morel sequential ligations and of the internal iliac arteries ligation are presented. The factors that hinder the success of these techniques also are reviewed. Vascular ligations are efficient strategies for hemorrhagic control during cesarean sections and should integrate the set of techniques that preserve the uterus in the treatment of postpartum hemorrhage.(AU)


Subject(s)
Humans , Female , Pregnancy , Uterine Artery/surgery , Postpartum Hemorrhage/surgery , Ligation/methods , Databases, Bibliographic , Fertility Preservation/methods , Postpartum Hemorrhage/mortality
13.
Ginecol. obstet. Méx ; 89(10): 779-789, ene. 2021. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1394365

ABSTRACT

Resumen OBJETIVO: Validar el rendimiento de la calculadora de la Fundación de Medicina Fetal 4.0 adaptada a población mexicana. MATERIALES Y MÉTODOS: Estudio de cohorte efectuado en embarazos con feto único, según el modelo de riesgos en competencia para preeclampsia en un centro de medicina fetal de la Ciudad de México. El riesgo a priori se calculó de acuerdo con la historia clínica. La presión arterial media, el índice de pulsatilidad medio de la arteria uterina y la proteína plasmática A asociada al embarazo se midieron a las 11 a 14 semanas de gestación con metodología estandarizada. El valor de cada marcador se transformó en múltiplos de la mediana adaptados a la población local. Se aplicaron la distribución normal multivariante y el teorema de Bayes para obtener las probabilidades posprueba individuales, que se utilizaron como clasificadores para el área bajo la curva de característica receptor-operador. RESULTADOS: La incidencia de preeclampsia fue del 5.0% (54/1078). El área bajo la curva de característica receptor-operador fue de 0.784 (0.712; 0.856) para preeclampsia a menos de 37 semanas y de 0.807 (0.762; 0.852) para preeclampsia global. CONCLUSIONES: La calculadora FMF 4.0 adaptada a población mexicana resultó válida. Si bien tuvo menor rendimiento al esperado para preeclampsia a menos de 37 semanas, el rendimiento para preeclampsia global fue satisfactorio. Se justifica desarrollar la calculadora local.


Abstract OBJECTIVE: To validate the performance of the Fetal Medicine Foundation 4.0 calculator adapted to the Mexican population. MATERIALS AND METHODS: Cohort study performed in singleton pregnancies, according to the competing risk model for preeclampsia in a fetal medicine center in Mexico City. The a priori risk was calculated according to the clinical history. Mean arterial pressure, mean uterine artery pulsatility index and pregnancy-associated plasma protein A were measured at 11 to 14 weeks of gestation with standardized methodology. The value of each marker was transformed into multiples of the median adapted to the local population. Multivariate normal distribution and Bayes' theorem were applied to obtain individual posttest probabilities, which were used as classifiers for the area under the receiver-operator characteristic curve. RESULTS: The incidence of preeclampsia was 5.0% (54/1078). The area under the receiver-operator characteristic curve was 0.784 (0.712; 0.856) for preeclampsia at less than 37 weeks and 0.807 (0.762; 0.852) for global preeclampsia. CONCLUSIONS: The FMF 4.0 calculator adapted to Mexican population proved valid. Although it had lower performance than expected for preeclampsia at less than 37 weeks, the performance for global preeclampsia was satisfactory. The development of the local calculator is justified.

14.
Rev. peru. ginecol. obstet. (En línea) ; 66(2): 00012, abr-jun 2020. graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1145002

ABSTRACT

RESUMEN La hemorragia posparto es una causa importante de mortalidad materna. La rotura del pseudoaneurisma de la arteria uterina es una lesión vascular con prevalencia desconocida que produce hemorragia posparto secundaria sin causa evidente. Puede ser potencialmente mortal, si no es diagnosticada y tratada adecuadamente. La etiología incluye traumatismo vascular durante la cesárea, parto vaginal, legrado o histerotomía. Su presentación clínica tiene variedad de síntomas que a menudo se asocian con otras patologías ginecológicas / obstétricas más frecuentes, con y sin sangrado vaginal, y puede abarcar desde ausencia de síntomas hasta hemorragia posparto severa con choque hipovolémico. Para evitar la hemorragia mortal, se debe hacer un diagnóstico rápido y preciso que muestre la naturaleza vascular de esta lesión. El diagnóstico está basado en estudios de imágenes no invasivos. En casos seleccionados adecuadamente, la embolización angiográfica es un método seguro y eficaz para controlar la hemorragia en pacientes hemodinámicamente estables y debe ser una opción antes de recurrir a la cirugía. Se describe un caso de rotura de pseudoaneurisma de arteria uterina posterior a cesárea.


ABSTRACT Postpartum hemorrhage is an important cause of maternal mortality. The rupture of a uterine artery pseudoaneurysm, a rare vascular lesion of unknown prevalence, produces secondary postpartum hemorrhage without an evident cause. If not properly diagnosed and treated, it can be life threatening. Etiology includes vascular trauma during cesarean section, vaginal delivery, curettage or hysterotomy. Its clinical presentation is varied and often associated with other more frequent gynecological and obstetric pathologies. Patients may present no symptoms, vaginal bleeding or even postpartum hemorrhage and hypovolemic shock. To prevent fatal bleeding, a rapid and accurate diagnosis must be made, based on non-invasive imaging studies. Angiographic embolization is a safe and effective method to control hemorrhage in hemodynamically stable patients and should be an option before resorting to surgery in selected cases. We describe a case of rupture of uterine artery pseudoaneurysm following a cesarean section.

15.
Rev. peru. ginecol. obstet. (En línea) ; 66(1): 25-30, ene.-Mar 2020. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1144980

ABSTRACT

ABSTRACT Objective : To establish the prognostic usefulness of cervical length and uterine artery pulsatility index for imminent preterm delivery in symptomatic patients. Design : Case-control study. Setting: Central Hospital "Dr. Urquinaona ", Maracaibo, Venezuela. Participants : Patients with preterm delivery within 7 days (group A) and pregnant women with preterm delivery within more than 7 days (group B). Methods : Cervical length and uterine artery pulsatility index were determined at hospital admission and all were followed until delivery. Main outcome measures: General characteristics, cervical length, uterine artery pulsatility index, imminent preterm delivery, and prognostic efficacy. Results : 119 participants were assigned to group A and 362 patients to group B. Cervical length was lower in group A, and the uterine artery pulsatility index was higher compared with group B (p <0.0001). Cervical length showed an area under the curve of 0.972, while the uterine artery pulsatility index presented an area under the curve of 0.843. The difference between the two measurements was significantly different between groups A and B (p <0.001). Combination of both measurements showed a significantly lower value in prediction capacity (0.987) compared with both measurements individually (p <0.0001). Conclusion : The combined use of cervical length and pulsatility index of the uterine artery was useful in the prediction of imminent preterm delivery in symptomatic patients.


RESUMEN Objetivo . Establecer la utilidad pronóstica de la longitud cervical e índice de pulsatilidad de la arteria uterina en el parto pretérmino inminente en pacientes sintomáticas. Diseño . Estudio de casos-controles. Institución. Hospital Central "Dr. Urquinaona", Maracaibo, Venezuela. Participantes . Pacientes con parto pretérmino en los siguientes 7 días (grupo A) y embarazadas con parto pretérmino más allá de los 7 días (grupo B). Métodos . Las mediciones de la longitud cervical e índice de pulsatilidad de la arteria uterina se realizaron al ingreso de las gestantes al hospital y todas fueron seguidas hasta el parto. Principales medidas de resultado. Características generales, longitud cervical, índice de pulsatilidad de la arteria uterina, parto pretérmino inminente y eficacia pronóstica. Resultados . 119 participantes fueron asignadas al grupo A y 362 pacientes al grupo B. La longitud cervical fue menor en el grupo A, mientras que el índice de pulsatilidad de la arteria uterina fue mayor comparado con el grupo B (p < 0,0001). La medición de la longitud cervical presentó un valor de área bajo la curva de 0,972, mientras que el índice de pulsatilidad de la arteria uterina mostró un área bajo la curva de 0,843. La diferencia de la diferencia entre ambas mediciones se consideró estadísticamente significativa (p < 0,001). La combinación de ambas mediciones tuvo un valor bajo la curva significativamente superior en capacidad de predicción (0,987) comparada con ambas mediciones en forma individual (p < 0,0001). Conclusión . El uso combinado de las mediciones de la longitud cervical y el índice de pulsatilidad de la arteria uterina resultó útil en la predicción de parto pretérmino inminente en pacientes sintomáticas.

16.
Rev. chil. obstet. ginecol. (En línea) ; 85(5): 526-536, 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1508003

ABSTRACT

INTRODUCCIÓN: La restricción del crecimiento intrauterino representa una importante morbimortalidad perinatal y cuya detección es variable según modelos clínicos y características propias en cada población. OBJETIVO: Evaluar si el Doppler de arterias uterinas y la edad materna conforman un modelo clínico con capacidad predictiva de restricción del crecimiento intrauterino en una amplia muestra de población peruana. MATERIALES Y MÉTODOS: Estudio observacional, analítico, de prueba diagnóstica. Participaron 1344 gestantes atendidas en un centro de referencia nacional materno perinatal Nivel III en Perú entre 2010-2018. La muestra fue seleccionada aleatoriamente y dividida en: muestra de entrenamiento y muestra para validación del mejor modelo clínico obtenido. Se usó análisis multivariado, medición de la capacidad diagnóstica y predictiva. RESULTADOS: El modelo clínico formado por el índice de pulsatilidad promedio mayor al percentil 95 de la arteria uterina y la edad materna mayor a 35 años conformo el modelo con el menor indicador de penalidad de Akaike en comparación con los otros modelos clínicos elaborados en el presente estudio, el índice de Youden fue 0.53. El área bajo la curva ROC fue de 0.75. Se obtuvo una sensibilidad de 71.5%, especificidad 72.1%, valor predictivo positivo 65.8%, valor predictivo negativo 91.2%. CONCLUSIONES: El uso del índice de pulsatilidad promedio de la arteria uterina asociado a la edad materna contribuyen a la formación de un modelo para discriminar RCIU; sin embargo, requiere de otros factores que permitan ajustar el modelo para una mayor tasa de detección.


INTRODUCTION: Intrauterine growth restriction represents an important perinatal morbimortality and its detection varies according to clinical models and characteristics of each population. OBJECTIVES: To evaluate if uterine artery Doppler and maternal age conform a clinical model with predictive capacity of intrauterine growth restriction in a wide sample of Peruvian population. MATERIALS AND METHOD: Observational, analytical, diagnostic test study. A total of 1344 pregnant women attended a national maternal perinatal reference center Level III in Peru between 2010-2018. The sample was randomly selected and divided: training sample and validation sample. In the analysis, multivariate analysis and measurement of diagnostic and predictive capabilities were applied. RESULTS: The clinical model formed by the average pulsatility index greater than the 95th percentile of the uterine artery and maternal age greater than 35 years made up the model with the lowest Akaike's penalty indicator compared to the other clinical models developed in the present study, Youden's index was 0.53. The area under the ROC curve 0.75. Sensitivity 71.5%, specificity 72.1%, positive predictive value 65.8%, negative predictive value 91.2%. CONCLUSIONS: The use of the average pulsatility index of the uterine artery associated with maternal age contributes to the formation of a model to discriminate IUGR; however, it requires other factors to adjust the model for a higher detection rate.


Subject(s)
Humans , Female , Pregnancy , Adolescent , Adult , Young Adult , Ultrasonography, Prenatal/methods , Ultrasonography, Doppler/methods , Uterine Artery/diagnostic imaging , Fetal Growth Retardation/diagnostic imaging , Blood Flow Velocity , Logistic Models , Predictive Value of Tests , ROC Curve , Sensitivity and Specificity , Gestational Age , Maternal Age , Fetal Growth Retardation/physiopathology
17.
J. vasc. bras ; 19: e20190149, 2020. tab, graf
Article in Portuguese | LILACS | ID: biblio-1135110

ABSTRACT

Resumo A embolização da artéria uterina (EAU) é um tratamento pouco invasivo e alternativo à cirurgia aberta no tratamento de miomatose uterina. Este estudo visa analisar a eficácia e a segurança da EAU nesses casos. Para isso, foi realizada uma revisão sistemática a partir de estudos disponíveis nas bases de dados MEDLINE/PubMed, LILACS e PEDro, via Biblioteca Virtual em Saúde. Foram encontrados 817 trabalhos; destes, 7 foram selecionados pelos critérios de elegibilidade (estudos analíticos, de corte longitudinal, retrospectivos ou prospectivos), totalizando 367 pacientes no estudo. As variáveis estudadas, bem como as características dos estudos incluídos, foram coletadas e armazenadas em um banco de dados. As taxas de redução do volume uterino e do mioma dominante foram 44,1% e 56,3%, respectivamente. A média do infarto completo do mioma dominante foi de 88,6% (82-100%). Quanto às complicações, a média obtida foi de 15±8,6 casos, sendo a maioria destas classificadas como menores, e nenhum óbito foi registrado. A média de reabordagem em valores absolutos foi de 12,2±15,5 casos. Portanto, a embolização da artéria uterina é um procedimento eficaz e com baixa taxa de complicações para o tratamento da leiomiomatose uterina na literatura analisada.


Abstract Uterine Artery Embolization (UAE) is a noninvasive alternative to open surgery for treatment of uterine myomatosis. This study aims to analyze the efficacy and safety of UAE in these cases. A systematic review was carried out of studies available on the Medline (via PubMed) and the LILACS and PEDro (via the Biblioteca Virtual em Saúde) databases. The searches found 817 studies, 7 of which were selected according to the eligibility criteria (analytical, longitudinal, retrospective, or prospective studies), with a total of 367 patients studied. The variables analyzed and the characteristics of the studies included were collated and input to a database. Rates of volume reduction of the uterus and the dominant myoma were 44.1% and 56.3%, respectively. Mean rate of complete infarction of the dominant myoma was 88.6% (82-100%). The mean number of complications observed was 15±8.6 cases, most of which were classified as minor, and no deaths were recorded. The mean number of re-interventions in absolute values was 12.2±15.5 cases. Therefore, in the literature analyzed, uterine artery embolization is an effective procedure with a low rate of complications for treatment of uterine leiomyomatosis.


Subject(s)
Humans , Female , Uterine Neoplasms , Uterine Artery Embolization/adverse effects , Leiomyoma , Efficacy , Endovascular Procedures
18.
Rev. peru. ginecol. obstet. (En línea) ; 65(2): 163-168, abr.-jun: 2019. tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1014510

ABSTRACT

Objective: To assess the diagnostic validity of the Doppler uterine artery pulsatility index (PI) and mean velocity (MnV) in preeclampsia (PE) and intrauterine growth restriction (IUGR). Design: Analytical cross-sectional study performed at the Hospital III Honorio Delgado in Arequipa, Peru, from May 2014 to April 2015. The group of cases consisted of 78 pregnant women with PE of early onset (< 34 weeks), late onset (≥ 34 weeks), IUGR and IUGR with PE, and the control group included 100 pregnant women 20 to 40 weeks gestation, with singleton pregnancies and no complications. PI and MnV of the uterine arteries, averages and diagnostic validity tests were calculated with Doppler ultrasound. MnV sensitivity and specificity were 76.2 and 96.9 respectively in IUGR, and 42.4 and 96.9 respectively in late onset PE. IP sensitivity and specificity were 28.6 and 92.2 respectively in IUGR, and 30.3 and 92.2 respectively in late onset PE. Conclusion: In this study of the uterine artery, Doppler mean velocity had higher sensitivity and specificity than pulsatility index for late onset PE and IUGR.


Objetivo. Valorar la validez diagnóstica del índice de pulsatilidad (IP) y velocidad media (VM) de la arteria uterina en la preeclampsia (PE) y la restricción del crecimiento intrauterino (RCIU). Diseño. Estudio transversal analítico realizado en el Hospital III Honorio Delgado de Arequipa, Perú, desde mayo 2014 hasta abril 2015. El grupo de casos lo constituyeron 78 gestantes con PE de inicio precoz (< 34 semanas), PE de inicio tardío (≥ 34 semanas), RCIU y RCIU con PE, y el grupo control estuvo formado por 100 gestantes sin complicaciones, con embarazo único de 20 a 40 semanas. Se realizó ecografía Doppler de las arterias uterinas, calculándose el IP y VM de las arterias uterinas, promedios y pruebas de validez diagnóstica en PE y RCIU. Resultados. La VM en la RCIU tuvo sensibilidad y especificidad de 76,2 y 96,9, respectivamente, y en la PE de inicio tardío, la sensibilidad y especificidad fueron 42,4 y 96,9, respectivamente. El IP en RCIU tuvo sensibilidad y especificidad de 28,6 y 92,2, respectivamente, y en PE de inicio tardío, la sensibilidad y especificidad fueron 30,3 y 92,2, respectivamente. Conclusiones. En el presente estudio de Doppler de la arteria uterina, la medición de la velocidad media tuvo más sensibilidad y especificidad que el índice de pulsatilidad, en la PE de inicio tardío y la RCIU.

19.
Femina ; 47(3): 175-180, 31 mar. 2019. ilus
Article in Portuguese | LILACS | ID: biblio-1046507

ABSTRACT

A hemorragia pós-parto é uma emergência obstétrica que acomete grande parcela de puérperas e leva à extensa quantidade de óbitos por ano. Entre as suas principais causas estão a atonia uterina e o acretismo placentário. Atualmente, as técnicas mais utilizadas para a resolução do sangramento se apresentam por muitas vezes ineficazes e/ou levam à infertilidade feminina. O presente estudo trata-se de uma revisão da literatura em modelo PRISMA, no qual foram selecionados 35 artigos dos últimos 12 anos, nas bases de dados do UpToDate, SciELO, PubMed, Plos ONE, Lilacs e Datasus, no qual serão apresentadas evidências de que, nas mãos de um profissional treinado, a embolização de artéria uterina se mostra como uma excelente alternativa no tratamento da hemorragia obstétrica, apresentando-se como terapêutica minimamente invasiva, com altas taxas de sucesso, baixo número de complicações e que preserva a função reprodutiva da mulher.(AU)


The post-partum hemorrhage is an obstetric emergency that affects a big percentage of women who have recently given birth and leads to a big amount of deaths per year. Its main causes are uterine atony and placentary accretism. Currently the main techniques for its resolution are the utilization of uterotonics and aggressive surgical approaches to the pelvic structure, which are commonly inefficient or bring long term injuries to the fertility. This study is a literature review structure on PRISMA model, where was selected 35 articles of the last 12 years, in these databases: UpToDate, SciELO, PubMed, Plos ONE, Lilacs and Datasus, in which will be presented evidences of, in expert professional hands, uterine artery embolization being an excellent alternative in the treatment of obstetric hemorrhage, presenting itself a minimally invasive technique, with high rates of success, low numbers of complications and the capacity of preserving the patient reproductive system.(AU)


Subject(s)
Humans , Female , Pregnancy , Uterine Artery Embolization/methods , Postpartum Hemorrhage/surgery , Postpartum Hemorrhage/mortality , Maternal Mortality , Databases, Bibliographic , Emergencies , Hysterectomy , Obstetric Labor Complications/surgery
20.
Rev. chil. obstet. ginecol. (En línea) ; 84(4): 320-325, 2019. graf, ilus
Article in Spanish | LILACS | ID: biblio-1058154

ABSTRACT

RESUMEN El pseudoaneurisma de arteria uterina es una causa de hemorragia puerperal poco frecuente y de gran gravedad cuya principal manifestación es el sangrado puerperal tardío. Esta complicación suele ocurrir de manera tardía tras una cirugía pélvica, aunque también está descrito tras el parto. La prueba de elección para el diagnóstico de esta complicación es la angiografía que permite además su tratamiento en el mismo acto, asociando una menor morbilidad y preservando la fertilidad de la paciente. Presentamos el caso de un pseudoaneurisma de arteria uterina tras cesárea cuya manifestación fue un hemoperitoneo masivo a los 17 días de la cesárea y que se resolvió mediante angiografía con embolización supraselectiva del mismo.


ABSTRACT Uterine artery pseudoaneurysm is a serious complication but an uncommon cause of postpartum haemorrhage which can mainly manifest as a severe bleeding in the late puerperium. This complication usually occurs after pelvic surgery, although it is also described after vaginal delivery. Angiography is the best diagnosis method which joins not only the diagnosis but also the treatment at the same moment, reducing the morbidity and preserving fertility. We report a case of a uterine artery pseudoaneurysm after cesarean delivery whose clinical manifestation was a massive haemoperitoneum after 17 days of the cesarean. It was treated by angiographic selective embolization of uterine artery pseudoaneurysm.


Subject(s)
Humans , Female , Pregnancy , Adult , Aneurysm, False/therapy , Aneurysm, False/diagnostic imaging , Hepatic Artery/pathology , Pregnancy Complications , Angiography , Cesarean Section
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